I am often asked what will be the next big pathogen of concern.  And I respond that I have no idea, except that it is already here just waiting to be recognized.  Indeed, it seems that some of our most noteworthy bugs appear abruptly out of nowhere.  How is that possible?  And if these bugs have been around for a long time, why hasn’t science recognized them?

Consider E. coli O157:H7 which was identified as a human pathogen in 1982, some 17 years after the serious complication it can cause, the hemolytic uremic syndrome (HUS) was first described by a

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